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为控制和消除白喉的发生,自1980年以来,进行了白喉免疫、疫情及带菌监测.现将1980年以来的监测结果报告如下:1 对象与方法1.1 免疫水平监测 在全区范围内随机抽取2～4、5～7、8～10、11～14、15～19、20～岁6个年龄组的不同人群,采末梢微量血0.3ml,分高血清-20℃冻存.由青岛市卫生防疫站采用间接血凝试验检测.白喉抗毒抗体≥0.0156IU/ml为阳性,为有保护水平.按《全国计划免疫技术管理规程》规定进行锡克氏试验.对百白破三联制剂基础免疫全程后1个月以上的婴儿监测免疫成功率.1.2 白喉带菌调查 连续8年在全区范围随机抽取2～4、5～7、11～14、15～19、20～岁5个年龄组人群采咽喉拭子,常规方法进行白喉杆菌的分离.分离菌株由山东省卫生防疫站鉴定.
To control and eliminate the occurrence of diphtheria, diphtheria immunization, outbreaks and surveillance of the incidence of diphtheria have been conducted since 1980. The monitoring results since 1980 are as follows: 1. Subjects and methods 1.1 Immunization level monitoring A random sample of 2 ~ 4,5 ~ 7,8 ~ 10,11 ~ 14,15 ~ 19,20 ~ 6 years of age groups of different populations, mining peripheral trace amount of blood 0.3ml, frozen in high serum -20 ℃ by the Qingdao Municipal Health Epidemic prevention station using indirect hemagglutination test. Diphtheria anti-drug antibody ≥ 0.0156IU / ml is positive, as a protective level. According to “National Plan of Immunization Technology Management Regulations” for Sikke’s test. Infants monitored more than one month after the completion of the surveillance of immune success rate.1.2 Diphtheria carrier bacteria survey for 8 consecutive years in the region randomly selected 2 ~ 4,5 ~ 7,11 ~ 14,15 ~ 19,20 ~ 5 years old age group Pluck throat swab, the conventional method for the separation of diphtheria bacilli isolated strains identified by the Shandong Provincial Health and Epidemic Prevention Station.