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动脉粥样硬化(Atherosclerosis,AS)是当今导致心脑血管疾病高发的主要因素,越来越多的报道说明中药葛根具有抗动脉粥样硬化的药理作用,其主要有效成分为异黄酮类化合物,以葛根素(puerarin)、大豆苷元(daidzein)和大豆苷(daidzin)研究最多,药理作用也最明显。文中对近年来葛根及其有效成分在动脉粥样硬化方面的研究进行综述。
Atherosclerosis (Atherosclerosis, AS) is the main factor leading to the high incidence of cardiovascular and cerebrovascular diseases. More and more reports indicate that Pueraria lobata has anti-atherosclerotic pharmacological effects. The main active ingredients are isoflavones, The most studied are puerarin, daidzein and daidzin, with the most pharmacological effects. In this paper, in recent years, pueraria and its active ingredients in the study of atherosclerosis are reviewed.