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目的:探讨不同年龄组高血压患者左室舒张功能变化对颈动脉血流动力学的影响。方法选择高血压患者608例,测量二尖瓣瓣口舒张期血流E峰及A峰,根据E峰及A峰的比值(E/A),按照E/A>1和E/A<1分成两组,两组内按年龄分为青年组、中年组和老年组,使用高频探头测量颈总动脉、颈内动脉及椎动脉的收缩期峰速度(PSV)、舒张末期流速(EDV)、阻力指数(RI)、搏动指数(PI)。结果三组高血压患者组间比较:E/A>1时,颈总动脉血流参数PSV、PI、RI随年龄的增长而降低。E/A<1时,颈总动脉PSV、EDV和椎动脉PSV均随年龄的增长而降低,颈总动脉和颈内动脉的PI、RI随年龄的增长而增高。E/A<1组与E/A>1组相比,老年组内颈总动脉、颈内动脉及椎动脉血流参数EDV下降,PI、RI升高。结论不同年龄的高血压患者,在左室舒张功能正常时仅表现为颈总动脉及椎动脉血流速度的减慢。在左室舒张功能减退时,表现为颈总动脉、颈内动脉和椎动脉的血流速度减慢及阻力的增大。而左室舒张功能正常与否,相较于青年组和中年组,对老年组患者颈动脉血流动力学的影响更加明显。左室舒张功能的损害在老年组加重了血管弹性或者功能的改变。“,”Objective To investigate the faction of left ventricular diastolic function to the hemodynamics of carotid artery in Patients with hypertension of dif erent age groups.Methods 608 cases of essential hypertension divided into three groups by age:Young-aged,middle-aged and elderly group.Measure the E、A of the diastolic mitral flow and the hemodynamics of carotid artery with Doppler echocardiography.Result Compared with the three age group of the essential hypertension:when E/A>1 ,some of the parameter of hemodynamics such as PSV、PI、RI were depressed along with the age growth in both CCA and VA;when E/A1 and E/A<1,EDV were depressed and the PI、RI were rised in the elder-aged group of the three groups of the carotid artery. Conclusion When the left ventricular diastolic function were decreased ,Vascular compliance were decrease and the resistance of blood flow rised along with the age growth.