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成年Ｗｉｓｔａｒ大鼠２０只，随机分为输精管结扎组（ＶＧ）和假手术组（ＳＯＧ）。术后第４个月检测了前列腺酸性磷酸酶（ＰＡＰ）等代表前列腺功能与肿瘤标志的酶学指标。结果表明，（１）血清ＰＡＰ活力，ＶＧ为４．９６±３．４Ｕ／ｍｌ，ＳＯＧ为５．６３±１．６９Ｕ／ｍｌ，两组无显著差异（Ｐ＞０．０５）；ＶＧ前列腺组织ＰＡＰ活力（１８．００±８．８１Ｕ／ｇ）略高于ＳＯＧ的（１５．０４±１１．９０Ｕ／ｇ），但无显著性。Ｐ／Ｔ百分比值ＶＧ为６５．０２±２５．３６％，ＳＯＧ为６８．６５±１１．６５％，Ｐ大于０．０５。（２）血清与前列腺组织碱性磷酸酶（ＡＬＰ）、乳酸脱氢酶（ＬＤＨ）与磷酸肌酸激酶（ＣＫ）活力，两组均无显著差异（Ｐ＞０．０５）。
Twenty adult Wistar rats were randomly divided into vasectomy group (VG) and sham operation group (SOG). At 4 months after surgery, the enzymatic parameters such as prostatic acid phosphatase (PAP), which represent prostate function and tumor markers, were examined. The results showed that: (1) The serum PAP activity of VG was 4.96 ± 3.4U / ml, SOG was 5.63 ± 1.69U / ml, there was no significant difference between the two groups (P> 0.05) PAP activity (18.00 ± 8.81 U / g) was slightly higher than that of SOG (15.04 ± 11.90 U / g) but not significant. P / T percentage value VG was 65.02 ± 25.36%, SOG was 68.65 ± 11.65%, P was greater than 0.05. (2) Alkaline phosphatase (ALP), lactate dehydrogenase (LDH) and creatine phosphokinase (CK) in serum and prostate tissue showed no significant difference between the two groups (P> 0.05).