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RU486是一种在受体水平上抗孕酮和糖皮质激素的人工合成类固醇,在较低等的哺乳动物中没有孕酮和糖皮质激素的激动作用以及雄激素和雌激素作用。作者报告不同剂量 RU486中止早孕的效果。经血清β-hCG 和妇科检查及停经不超过42天正常妊娠的37名健康妇女,口服25mg、50mg 和100mg 三种不同剂量水平的 RU486,每天2次,午前和午后8~10时各一次,共4天。服药前4小时和服药后1小时禁食。所有病例都在治疗开始后的
RU486 is an artificially synthesized steroid that is resistant to progesterone and glucocorticoids at the receptor level without the agonism of progesterone and glucocorticoids and the androgen and estrogen effects in the lower mammals. The authors report the effect of different doses of RU486 on termination of early pregnancy. Thirty-seven healthy women who underwent serum β-hCG and gynecological examinations and normal pregnancy less than 42 days were orally administered RU486 at three dosage levels of 25 mg, 50 mg and 100 mg twice daily, 8 to 10 o’clock in the afternoon and one in the afternoon, A total of 4 days. 4 hours before taking medicine and 1 hour after taking fasting. All cases are after treatment begins