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目的:提高临床对原发性肾上腺恶性淋巴瘤(PAL)的诊治水平。方法:报告收治的3例PAL患者的临床资料,3例的临床表现和影像学检查均无特异性。2例经手术探查明确诊断,1例在CT导引下行肿瘤穿刺活检后明确诊断。病理检查均诊为弥漫型、大B细胞性肾上腺非霍奇金PAL,术后均常规行CHOP化疗。结果:1例患者随访1年后失访,另2例分别于诊断后1年8个月、5年2个月死亡。结论:PAL恶性度较高,预后不良,临床表现和影像学检查缺乏特异性,CT或超声导引下的活检穿刺是明确诊断的好方法,手术及化疗对PAL有效。
Objective: To improve clinical diagnosis and treatment of primary adrenal lymphoma (PAL). Methods: The clinical data of 3 cases of PAL patients reported in the report, 3 cases of clinical manifestations and imaging studies were not specific. Two cases were confirmed by surgical exploration, and one case was confirmed by CT guided tumor puncture biopsy. Pathological examination were diagnosed as diffuse, large B cell adrenal non-Hodgkin PAL, postoperative routine CHOP chemotherapy. Results: One patient was followed up one year later and the other two patients were killed at 1 year and 8 months after diagnosis and at 2 years after 5 years. Conclusions: PAL has high malignancy and poor prognosis, and its clinical manifestations and imaging examination are not specific. CT or ultrasound-guided biopsy is a good way to confirm the diagnosis. Surgical and chemotherapy are effective for PAL.