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目的探讨宫颈液基薄层细胞学(TCT)及阴道镜下活检组织病理学对宫颈病变的诊断价值。方法回顾性分析329例液基细胞学筛查及相应组织病理结果。结果 TCT检查结果中,低度鳞状上皮内病变(LSIL)与低级别宫颈上皮内瘤变(CINI)的KAPPA值为0.068;高度鳞状上皮内病变(HSIL)与高级别宫颈上皮内瘤变(CINⅡ、CINⅢ)KAPPA值为0.465;TCT结果显示,不典型鳞状上皮细胞(ASCUS)为21.0%(69/329),其中CIN占10.1%(7/69)。湿疣样增生占27.4%(90/329)。结论 TCT检查结果中,LSIL与CINⅠ有一致性,HSIL与CINⅡ、CINⅢ有良好的一致性;36～45岁女性是CIN的高发人群。应重视ASCUS和湿疣样增生的临床管理。
Objective To investigate the value of cervical cytology (TCT) and colposcopic biopsy histopathology in the diagnosis of cervical lesions. Methods A retrospective analysis of 329 cases of liquid-based cytology screening and the corresponding histopathological findings. Results The KAPPA value of low grade squamous intraepithelial lesion (LSIL) and low grade cervical intraepithelial neoplasia (CINI) was 0.068 in TCT test results. High grade squamous intraepithelial lesion (HSIL) was associated with high grade cervical intraepithelial neoplasia (CINⅡ, CINⅢ) KAPPA value of 0.465; TCT results showed that atypical squamous epithelial cells (ASCUS) was 21.0% (69/329), of which CIN accounted for 10.1% (7/69). Condyloma-like hyperplasia accounted for 27.4% (90/329). Conclusions The results of TCT showed that LSIL was consistent with CINⅠ, HSIL had good consistency with CINⅡ and CINⅢ, while women aged 36-45 were high incidence of CIN. ASCUS and genital warts should pay attention to the clinical management of hyperplasia.