心力衰竭是临床最常见的心血管疾病之一,当前针对病理生理变化的药物治疗只能部分缓解症状和降低死亡率。近年来随着冠心病急性期死亡率的下降和人口老龄化,慢性心力衰竭的发病率增加了2倍以上,不良预后与恶性肿瘤相当。目前随着载体技术、转基因技术的发展、完善,以及应用导管 Heart failure is one of the most common cardiovascular diseases in clinical practice. Current pharmacological treatments for pathophysiological changes only partially relieve symptoms and reduce mortality. In recent years, with the decline in the mortality rate of acute coronary heart disease and population aging, the incidence of chronic heart failure increased more than 2 times, the adverse prognosis and malignant tumors. Currently with the carrier technology, the development of transgenic technology, improve, and the application of catheter