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目的分析热化疗治疗晚期肺癌胸腔积液的临床效果。方法随机将50例晚期肺癌胸腔积液患者均分为研究组与对照组,各自25例,对照组采用顺铂化疗,而研究组在对照组方式上加用热化疗,对比分析两组患者临床效果及毒副反应情况。结果研究组总有效率为84.00%(21/25),对照组则为68.00%(17/25),组间对比差异有统计学意义(P<0.05);研究组毒副反应发生率为8.00%(2/25),对照组则为20.00%(5/25),组间对比差异有统计学意义(P<0.05)。结论晚期肺癌胸腔积液患者采用热化疗可以取得比较良好的效果,临床疗效显著,安全性更高,值得借鉴。
Objective To analyze the clinical effect of thermochemotherapy on advanced lung cancer with pleural effusion. Methods A total of 50 patients with advanced lung cancer with pleural effusion were randomly divided into study group and control group, with 25 patients in each group. Cisplatin was used as the control group, while the study group was treated with thermochemotherapy in the control group. The clinical data of two groups were compared Effects and side effects. Results The total effective rate was 84.00% (21/25) in the study group and 68.00% (17/25) in the control group, with significant difference between the two groups (P <0.05). The incidence of adverse reactions in the study group was 8.00 % (2/25) in the control group and 20.00% (5/25) in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusions The treatment of advanced lung cancer with pleural effusion by thermochemotherapy can achieve better results, with significant clinical efficacy and safety, which is worth learning from.