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应用大鼠营养性肥胖模型，研究中药参减肥粉减肥作用及其帆理。结果表明参减肥粉可降低Ｌｅｅ’ｓ指数和脂肪系数；降低血中和肝脏的ＴＧ水平；降低血糖；增加血胰岛素和雌二醇的水平。其减肥机理与调节脂质代谢和糖代谢有关；与增加雌二醇和胰岛素水平有关；不影响血睾酮、皮质醇、ｃＡＭＰ和ｃＡＭＰ／ｃＧＭＰ水平，也不影响α－淀粉酶活性。
The rat model of nutritional obesity was used to study the effect of Chinese herbs on weight loss and its treatment. The results showed that a reference to reduce the fat powder can reduce Lee’s index and fat factor; lower blood and liver TG levels; lower blood sugar; increase blood insulin and estradiol levels. The mechanism of weight loss is related to the regulation of lipid metabolism and glucose metabolism; it is related to the increase of estradiol and insulin levels; it does not affect the levels of blood testosterone, cortisol, cAMP and cAMP / cGMP nor affect the activity of α-amylase.