日本并咪唑类药物问世以来,甲苯咪唑、阿苯达唑试用治疗蛲虫病均取得满意疗效,但上述2药经动物实验,均具致畸作用,孕妇忌用。1974年研制成一种苯并米唑类药物称芬苯达唑(fenbendazole),是一种广谱、高效而安全的抗蠕虫新药,国外已试用于临床,作者尚未见国内有报道。现将1987年来试用于治疗蛲虫病36例报道如下。其结构式如图1。 Japan and imidazole drugs since the advent of mebendazole, albendazole trial treatment of enterobiasis have achieved satisfactory results, but the above two drugs by animal experiments, both teratogenic effects, pregnant women hanged. Developed in 1974 as a benzimidazole drug fenbendazole (fenbendazole), is a broad-spectrum, efficient and safe new worm-resistant drugs, has been tested in clinical practice abroad, the author has not yet been seen in the country. Now try to try to treat enterobiasis in 1987 36 cases are reported below. The structural formula shown in Figure 1.