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目的 :分析呼吸内科患者下呼吸道感染病原菌及药敏情况。方法 :以我院2010年1月-2014年3月呼吸内科患者中下呼吸道感染1500例患者为研究对象,结合痰菌培养和药敏结果进行回顾性分析。结果 :培养1500例下呼吸道感染患者的痰液,获得650株病原菌,经检测,株呈阳性反应,总阳性率为51.0%;在此650株病原菌中,437株为革兰氏阴性菌杆菌;118株为革兰氏阳性球菌;其余95株为真菌。药敏性:革兰阴性杆菌均对舒巴坦、阿米卡星、亚胺培南等药物有敏感性;其中,肺炎链球菌对左氧氟沙星、亚胺培南等药物有敏感性,葡萄球菌对万古霉素药物有敏感性。结论 :革兰氏阴性杆菌较之革兰氏阳性球菌、真菌是造成患者下呼吸道感染的最大病因,因此,应在临床用药中优先选择抗菌药物,控制用药次数,以降低病菌的耐药性。
Objective: To analyze the pathogenic bacteria and drug susceptibility of lower respiratory tract infection in respiratory medicine patients. Methods: 1500 patients with lower respiratory tract infection in respiratory medical patients from January 2010 to March 2014 in our hospital were selected as the research objects. The sputum culture and drug susceptibility results were retrospectively analyzed. Results: 1500 sputum samples from patients with lower respiratory tract infection were obtained and 650 strains of pathogens were obtained. The positive rate was 51.0% after being tested. Among the 650 pathogenic bacteria, 437 were Gram-negative bacilli. 118 strains of Gram-positive cocci; the remaining 95 strains of fungi. Susceptibility: Gram-negative bacilli are sulbactam, amikacin, imipenem and other drugs are sensitive; among them, Streptococcus pneumoniae levofloxacin, imipenem and other drugs are sensitive to Staphylococcus aureus Vancomycin drugs are sensitive. Conclusion: Gram-negative bacilli are the most important cause of lower respiratory tract infection in patients with Gram-positive bacilli. Therefore, antibacterials should be given priority in clinical treatment to reduce the drug resistance of pathogens.