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目的:探讨和分析纳洛酮在抢救治疗急性酒精中毒中的应用效果。方法:此次研究选择我院急救中心在2016年1月-2016年7月期间收治的150例急性酒精中毒患者作为研究主体,按患者入院顺序分为甲组和乙组,其中甲组患者为77例,乙组患者为73例,均给予甲乙两组患者常规治疗,甲组患者加用纳洛酮进行治疗,对比甲乙两组患者的起效时间、清醒时间。结果:甲组患者的起效时间少于乙组患者,差异对比存在统计学意义(t=58.347,P=0.000)。甲组轻度、中度、重度中毒患者的清醒时间均少于乙组的轻度、中度、重度中毒患者,差异对比存在统计学意义(t=15.867、10.698、14.153,P=0.000)。结论:纳洛酮在抢救治疗急性酒精中毒中的应用效果确切,起效时间很快,并且可快速使患者清醒,值得推广。
Objective: To investigate and analyze the effect of naloxone in the treatment of acute alcoholism. Methods: The study selected our emergency center in January 2016-July 2016 period of 150 cases of acute alcoholism patients as the main body of study, according to the order of patients admitted to Group A and Group B, in which patients in Group A 77 cases, B group of 73 patients were given conventional treatment of patients with both A and B, patients with naloxone plus A group of patients treated, compared to two groups of patients with onset and awake time. Results: The onset time of patients in group A was less than that in group B, the difference was statistically significant (t = 58.347, P = 0.000). Patients with mild, moderate and severe poisoning in group A had less awake time than those with mild, moderate and severe poisoning in group B, and the difference was statistically significant (t = 15.867,10.698,14.153, P = 0.000). Conclusion: Naloxone is effective in salvage treatment of acute alcoholism, its onset time is very fast, and it can make the patients awake quickly and is worth popularizing.