论文部分内容阅读
目的评价醒脑静和纳洛酮联合应用治疗脑出血后昏迷的临床效果。方法 96例急性脑出血昏迷患者,随机分为治疗组和对照组,每组48例。两组患者均采用常规综合对症支持治疗,对照组在常规治疗基础上采用纳洛酮治疗,治疗组在对照组治疗基础上采用联合醒脑静治疗。治疗14 d后,比较两组治疗前后神经功能缺损评分和Barthel指数评分以及临床疗效。结果治疗后,两组神经功能缺损评分明显降低,Barthel指数均明显升高(P<0.05);与对照组治疗后比较,治疗组神经功能缺损评分降低更加明显,Barthel指数升高更加明显(P<0.05);与对照组比较,治疗组总有效率明显较高(89.58%VS72.92%),差异有统计学意义(P<0.05)。结论醒脑静联合纳洛酮治疗急性脑出血昏迷,可以显著的改善患者的神经功能,提高生活质量以及临床疗效,能够大力在临床上推广应用。
Objective To evaluate the clinical effect of combination of xingnaojing and naloxone in the treatment of coma after intracerebral hemorrhage. Methods 96 patients with cerebral hemorrhage coma were randomly divided into treatment group and control group, 48 cases in each group. The patients in both groups were treated with conventional comprehensive symptomatic and supportive treatment. The control group was treated with naloxone on the basis of routine treatment. The treatment group was treated with combination of xingnaojing on the basis of the control group. After 14 days of treatment, neurological deficit scores and Barthel index scores and clinical efficacy were compared between the two groups before and after treatment. Results After treatment, the score of neurological deficit and the Barthel index in the two groups were significantly increased (P <0.05). Compared with the control group, the neurological deficit score of the treatment group decreased more obviously and the Barthel index increased more significantly (P <0.05). Compared with the control group, the total effective rate of the treatment group was significantly higher (89.58% VS72.92%), the difference was statistically significant (P <0.05). Conclusion Xingnaojing combined with naloxone in the treatment of acute cerebral hemorrhage coma can significantly improve the neurological function, improve quality of life and clinical efficacy, which can be widely applied in clinic.