人体循环的脂蛋白按其水合物密度分为五类:乳糜微粒、极低密度脂蛋白(VLDL)、中密度脂蛋白(IDL)、低密度脂蛋白(LDL)、和高密度脂蛋白(HDL).脂蛋白十分重要,因为它与甘油三脂、磷脂和胆固醇的转运和代谢有关.目前已分离出了八种脱辅基脂蛋白(apo),它们是:apoAⅠ、AⅡ、AⅣ、B、CⅠ、CⅡ、CⅢ和E.除apoB外,所有脱辅基脂蛋白的顺序都已清楚,它们都含有与水和脂环境相互作用的同源的两性α-螺旋区域.因此,有人主张apo蛋白质是由同一祖先重复而成的.apoAⅠ、 Human circulating lipoproteins are classified into five groups according to their hydrate density: chylomicrons, VLDL, IDL, LDL, and HDL (HDL) Lipoproteins are important because they are involved in the transport and metabolism of triglycerides, phospholipids, and cholesterol, and eight apolipoproteins have been isolated and are now apoAI, AII, AIV, B, C I, C II, C III and E. All apolipoproteins, except for apoB, are well known and contain homologous a-helical α-helical regions that interact with water and the lipid environment.Therefore, it has been suggested that apo proteins Is repeated by the same ancestor .apoA Ⅰ,