通过对急性心肌梗塞（ＡＭＩ）早期（自胸痛到冠脉溶栓开始＜１２小时）患者１５例（治疗组，其中男性１３例，女性２例，平均年龄５４．１３±５．９４岁，前壁梗塞７例，下壁梗塞７例，高侧壁梗塞１例）行冠状动脉内溶栓治疗（治疗组），并与１６例非溶栓治疗患者（对照组，其中男性１２例，女性４例，平均年龄为６２．１８±６．３５岁，前壁梗塞１１例，下壁梗塞５例）比较。结果：治疗组在发病后两周ＵＣＧ示左房内径为３４．７４±３．６３ｍｍ，左室内径５１．２０±４．９１ｍｍ，左室射血分数（ＥＦ）为０．６３±０．１１，明显优于对照组的左房内径３９．９３±３．２１ｍｍ，左室内径５６．４４±５．４７ｍｍ，ＥＦ０．５２±０．１５；运动试验：治疗组１５例中阳性７例，对照组１６例中阳性１１例；经冠脉成形术后运动试验均阴性。从而说明急性心肌梗塞冠脉再通治疗是防止梗塞后心脏几何形状变形（即心室结构重建），从而保存心脏整体与节段的功能，提高梗塞后远期存活率的重要治疗手段。 Fifteen patients (13 males and 2 females, mean age 54.13 ± 5.94 years, mean age at onset 7 cases of wall infarction, 7 cases of inferior wall infarction and 1 case of high side wall infarction) underwent coronary thrombolysis (treatment group), and 16 patients without thrombolysis (control group, including 12 males and 4 females For example, the average age was 62.18 ± 6.35 years old, 11 cases of anterior wall infarction, 5 cases of inferior wall infarction). Results: UCG showed 34.74 ± 3.63mm in left atrium, 51.20 ± 4.91mm in left ventricle, and 0.63 ± 0.11 in left ventricle , Significantly better than the control group left atrium diameter 39.93 ± 3.21mm, left ventricular diameter 56.44 ± 5.47mm, EF0.52 ± 0.15; exercise test: the treatment group of 15 cases in the positive 7 cases, control Group of 16 cases were positive in 11 cases; after coronary angioplasty motor test were negative. This shows that acute myocardial infarction coronary recanalization therapy is to prevent the deformation of the heart geometry after infarction (ie, ventricular structural remodeling), thereby preserving the function of the whole heart and segments, improve long-term survival after infarction, an important treatment.