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Among 58 consecutive patients who underwent electrophysiologic testing for ris k assessment and who subsequently received a third-generation implantable cardi overter-defibrillator, 39 had ventricular tachycardia induced in the baseline s tate and 19 had ventricular tachycardia induced only after administration of int ravenous procainamide, increasing the yield of electrophysiologic risk assessmen t by 49%. At follow-up, ventricular arrhythmias requiring implantable cardiove rter-defibrillator termination occurred in 14 of 39 patients inducible in the b aseline state and in 7 of 19 patients inducible only with intravenous procainami de. The provocative use of intravenous procainamide during electrophysiologic ri sk assessment increases the detection rate for risk of sustained ventricular arr hythmias with no loss of positive predictive value.
Among 58 consecutive patients who underwent electrophysiologic testing for ris k assessment and who up received a third-generation implantable cardi overter-defibrillator, 39 had ventricular tachycardia induced in the baseline s tate and 19 had ventricular tachycardia induced only after after administration of int ravenous procainamide, increasing the yield of electrophysiologic risk assessmen t by 49%. At follow-up, ventricular arrhythmias requiring implantable cardiove rter-defibrillator for <"> termination of in 14 of 39 patients inducible in the b aseline state and in 7 of 19 patients inducible only with intravenous procainami de The provocative use of intravenous procainamide during electrophysiologic ri sk assessment increases the detection rate for risk of sustained ventricular arr hythmias with no loss of positive predictive value.