目的:探讨针对小儿高原性心脏病(HAHD)合并心力衰竭患儿,采用盐酸曲美他嗪完成治疗后的临床效果表现。方法:选取我院2011年12月—2013年12月小儿HAHD合并心力衰竭患儿164例。由随机数表法完成所有患儿的随机分组。设为C1组(治疗组84例)与C2组(对照组80例)。C2组:常规药物治疗;C1组:常规药物治疗+盐酸曲美他嗪进行治疗。C1组与C2组患儿完成3个月的治疗后,对所有患儿实施6min步行试验,选择超声心动图对患儿LVEF(左室射血分数)以及LVED(左室舒张末期内经)进行评估。结果:C1组与C2组患儿分别完成3个月的治疗后,对患儿实施6min步行试验发现,C1组步行距离多于C2组患儿非常明显(P<0.05);在LVED方面,C1组低于C2组患儿非常明显(P<0.05);在LVEF方面,C1组高于C2组患儿非常明显(P<0.05);结论:针对小儿HAHD合并心力衰竭患儿,选择盐酸曲美他嗪进行治疗,可以显著改善患儿的心功能,有效提高患儿的生存质量。 Objective: To investigate the clinical effect of pediatric patients with heart disease complicated with heart failure (HAHD) treated with trimetazidine hydrochloride. Methods: A total of 164 children with HAHD complicated with heart failure in our hospital from December 2011 to December 2013 were selected. All patients were randomized by random number table. Set C1 (treatment group 84 cases) and C2 group (80 cases of control group). Group C2: conventional drug treatment; Group C1: conventional drug therapy + trimetazidine hydrochloride treatment. After completion of 3 months of treatment in children in group C1 and group C2, a 6-minute walk test was performed on all children and echocardiography was used to assess LVEF and LVED in children. . Results: After 3 months of treatment in C1 group and C2 group, respectively, the 6-minute walking test in children showed that the walking distance in C1 group was significantly higher than that in C2 group (P <0.05); in LVED, C1 In LVEF group, C1 group was higher than C2 group (P <0.05) .Conclusion: In children with HAHD complicated with heart failure, we selected trimetazidine hydrochloride Hisiazine for treatment, can significantly improve children’s heart function, effectively improve the quality of life of children.