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内皮素ＥＴ－１主要是由血管内皮合成和释放的强烈收缩血管活性肽。本文旨在研究６５４－２对内毒素性肺损伤时内皮素－１（ＥＴ－１）ｍＲＮＡ表达的影响。１ 资料与方法１－１ 动物分组 雄性健康ＳＤ大鼠２１只，体重１８０～２３０ｇ。随机等分成对照组、内毒素组和６５
Endothelin ET-1 is predominantly a vasoconstrictive vasoactive peptide that is synthesized and released by the vascular endothelium. This article aims to investigate the effect of 654-2 on endothelin-1 (ET-1) mRNA expression in endotoxin-induced lung injury. 1 Materials and Methods 1-1 animal group of 21 male healthy SD rats weighing 180 ~ 230g. Randomly divided into control group, endotoxin group and 65