以辐射热甩尾法测定大鼠痛阈为指标,观察脑室注射三肽-促甲状腺素释放激素(TRH)10μg/20μl对电针(强度为1、2、3伏)大鼠双侧“足三里”、“三阴交”和皮下注射吗啡(2、4、6mg/kg)引起的镇痛效应的影响。实验结果表明,脑室注射TRH不影响正常情况下大鼠的辐射热甩尾反应,但能对抗强度为2、3伏的电针镇痛和剂量为2、4mg/Kg的吗啡镇痛效应。 Rats’ pain threshold was measured by radiant heat tail-flicking method. The intracerebroventricular injection of tripeptide-TRH (10 μg/20 μl) was used to observe the bilateral “foot” of rats with electroacupuncture (intensity of 1, 2, and 3 volts). Effects of analgesia caused by Sanli”, “Sanyinjiao” and subcutaneous morphine (2, 4, and 6 mg/kg). The experimental results showed that intraventricular administration of TRH did not affect the radiant heat tail flick reaction in normal rats, but it could resist the electroacupuncture analgesia with intensity of 2, 3 volts and the morphine analgesic effect with a dose of 2, 4 mg/Kg.