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目的:研究ABO血型不合异基因外周血造血干细胞移植的护理措施。方法:我院选择2011年5月至2015年5月间诊治的20例ABO血型不合异基因外周血造血干细胞移植患者,对其临床资料进行分析。结果:所选的5例患者中,4例患者恢复了正常的造血功能,血型转变为完全供者型,1例患者白细胞血小板恢复,但是红细胞植入延迟。所选的患者在输注移植物时未见有短暂的血红蛋白尿,无严重急性溶血和迟发性溶血出现,1例出现严重的移植物抗宿主病。结论:移植是一项巨大的工程,特别是对ABO血型不合异基因造血干细胞移植来说。层流病房的护理人员需要掌握扎实的临床技能和理论知识,加强护理工作质量,密切观察患者贫血症状及溶血反应对抑制成功率影响较大,应引起重视。
Objective: To study the nursing measures of ABO incompatible peripheral blood hematopoietic stem cell transplantation. Methods: Twenty patients with ABO-incompatible peripheral blood hematopoietic stem cell transplant who were diagnosed and treated between May 2011 and May 2015 in our hospital were selected and their clinical data were analyzed. RESULTS: Of the 5 patients selected, 4 returned to normal hematopoietic function, their blood type became completely donor, 1 had white blood cell platelet recovery, but delayed erythrocyte implantation. Selected patients had no transient hemoglobinuria, no severe acute haemolysis, and delayed hemolysis on graft transfusions, and one developed severe graft-versus-host disease. Conclusion: Transplantation is a huge project, especially for ABO-incompatible allogeneic hematopoietic stem cell transplantation. Nurses in laminar flow wards need to acquire solid clinical skills and theoretical knowledge, enhance the quality of nursing work, and closely observe the symptoms and hemolysis of patients with anemia and have a greater impact on the success rate of suppression.