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作者作了两项研究。第一项研究了14例白人遗传性血色病和60例继发性铁负荷过量;第二项研究了49例非洲黑人铁质沉积症,测定了转铁蛋白饱和度、血清铁蛋白、血清转铁蛋白受体浓度等项指标。均以铁蛋白>400μg/L为纳入标准。 结果 在第一项研究中,血色病组血清铁蛋白几何均数752μg/L,明显高于继发性铁负荷过量者(590μg/L,P<0.05);血色病组有2例,继发性铁负荷过量组有3例血清转铁蛋白受体浓度高于正常
The author made two studies. The first studied 14 cases of white hereditary hemochromatosis and 60 cases of secondary iron overload; the second studied 49 cases of African black iron deposition disease, measured the transferrin saturation, serum ferritin, seroconversion Ferritin receptor concentration and other indicators. Ferritin> 400μg / L were included in the standard. Results In the first study, the geometric mean of serum ferritin was 752μg / L in hemochromatosis group, which was significantly higher than that in secondary iron overload (590μg / L, P <0.05); in hemochromatosis group, 2 cases were secondary Three patients with iron overload had serum transferrin receptor concentrations higher than normal