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目的研究主动脉根部宽度(ARD)与脑梗死(CI)的关系。方法选择155例CI病人及84例正常对照者,使用二维超声在心室收缩期测量主动脉根部内径宽度(ARD)。测量血压、空腹血糖、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)等生化指标。结果CI病人ARD[(29.5±2.6)mm]高于对照组[(27.3±2.2)mm](P<0.01)。CI病人血压、TC及LDL水平均高于对照组(P<0.05)。多因素logistic回归分析显示ARD是CI发病的独立危险因素(OR1.48,95%CI:1.15～1.90,P<0.01)。结论ARD与CI有较好的相关性,主动脉粥样硬化是CI的重要危险因素。
Objective To study the relationship between aortic root width (ARD) and cerebral infarction (CI). Methods A total of 155 patients with CI and 84 healthy controls were enrolled in the study. Aortic root width (ARD) was measured by ventricular systole using two-dimensional echocardiography. Blood pressure, fasting blood glucose, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) and other biochemical indicators were measured. Results CI patients ARD [(29.5 ± 2.6) mm] higher than the control group (27.3 ± 2.2) mm] (P <0.01). The blood pressure, TC and LDL levels in CI patients were higher than those in control group (P <0.05). Multivariate logistic regression analysis showed that ARD was an independent risk factor for CI (OR 1.48, 95% CI: 1.15-1.90, P <0.01). Conclusions There is a good correlation between ARD and CI. Atherosclerosis is an important risk factor of CI.