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目的:探讨多次机采血小板对献血者血小板功能的影响。方法:收集2014年2月至2015年2月广州血液中心采集血小板的60例献血者为研究对象,30例连续固定献血者为观察组,另30例首次献血者为对照组,比较两组献血者的血小板功能。结果:采血前,观察组和对照组的血栓弹力图(thromboela-stogram,TEG)R值、K值、α角及MA值比较,差异无统计学意义(P>0.05);采血后,观察组和对照组的R值、K值、α角及MA值有所改变,其中K值、α角、MA值与采血前相比,差异具有统计学意义(P<0.05),但组间比较,差异无统计学意义(P>0.05)。结论:多次机采血小板后,献血者的血小板数量及功能仍处于正常范围,未影响血小板的采集质量及献血者的健康,满足了临床用血的需求。
Objective: To investigate the effect of multiple platelet-harvesting on platelet function in blood donors. Methods: Sixty blood donors collected from Guangzhou Blood Center from February 2014 to February 2015 were selected as study subjects. Thirty consecutive patients with fixed blood donors were selected as the observation group and the other 30 first-time donors as control group. Blood donation was compared between the two groups The platelet function. Results: Before blood sampling, there was no significant difference in R value, K value, α angle and MA value of thromboela-stogram (TEG) between the observation group and the control group (P> 0.05) (P <0.05). However, the values of R, K, α, and MA in the control group were significantly different from those in the control group (P <0.05) The difference was not statistically significant (P> 0.05). Conclusion: After collecting blood platelets for many times, the number and function of platelets in blood donors are still in the normal range without affecting the quality of platelet collection and the health of blood donors, meeting the need of clinical blood supply.