The conditions of preparation and performance of a new structure of cationic organic polymeric micropaticles (CPMP) mainly composed of styrene and DADMAC were studied. And its application on retention and drainage on bleached hardwood pulp was investigated and compared with that of APAM and CPAM. The results show that the retention and drainage of CPMP on pulp is in positive proportion to the rise of the potential of the solution, and the first-pass retention ratio of bleached hardwood pulp goes up with the increase of the CPMP content. The functions of CPMP and CPAM are affected less by the shear force and the pH value of the system compared to that of APAM, and effect on retention of CPMP3 is appropriate to that of CPAM, but superior to that of APAM.