论文部分内容阅读
目的探讨降钙素原(PCT)检测在小儿细菌感染性疾病中的诊断意义。方法选取2012—2013年保定市儿童医院儿科收治的感染性疾病患儿102例,根据病原学或血清免疫学检测结果分为细菌感染组(观察组)和病毒感染组(对照组),每组51例。采用免疫荧光的方法检测两组患者血清降钙素原含量。观察两组患者的血清PCT含量。结果观察组患者PCT<0.5μg/L比例小于对照组,≥0.5μg/L的比例高于对照组,差异有统计学意义(P<0.05)。观察组PCT阳性率为72.6%(37/51),高于对照组的43.1%(22/51),差异有统计学意义(P<0.05)。结论血清PCT含量的测定有助于区分儿童感染性与非感染性疾病,是确诊细菌感染与否的敏感标志物之一。
Objective To investigate the diagnostic value of procalcitonin (PCT) detection in pediatric bacterial infectious diseases. Methods A total of 102 children with infectious diseases admitted to Children’s Hospital of Baoding from 2012 to 2013 were selected and divided into bacterial infection group (observation group) and virus infection group (control group) according to the results of etiological or serum immunological tests. Each group 51 cases. Immunofluorescence method was used to detect serum procalcitonin levels in two groups. The serum PCT levels in two groups were observed. Results The proportion of PCT <0.5μg / L in the observation group was less than that in the control group, and the ratio of ≥ 0.5μg / L was higher than that in the control group (P <0.05). The positive rate of PCT in the observation group was 72.6% (37/51), which was higher than that in the control group (43.1%, 22/51), the difference was statistically significant (P <0.05). Conclusion The determination of serum PCT levels can help distinguish infectious and non-infectious diseases in children and is one of the sensitive markers for the diagnosis of bacterial infection.