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目的:对比研究序贯放化疗与单纯化疗应用于老年局部晚期非小细胞肺癌治疗的效果。方法:选择病例数共77例,来源于2012年7月-2014年8月本院收治的门诊及出院患者,全部患者均满足非小细胞肺癌诊断标准,随机分为治疗组38例和对照组39例,前组病人应用序贯放化疗治疗,后组病人应用单纯化疗治疗,对比两组治疗效果和不良反应发生情况。结果:经一段时间的治疗,治疗组总有效率可达81.6%,与对照组相比明显要高,差异显著,P<0.05。两组在不良反应发生率上,差异不明显,P>0.05。结论:在老年局部晚期非小细胞肺癌临床治疗中,较单纯化疗而言,应用序贯放化疗进行治疗,治疗效果更为显著,应用价值和推广价值均比较高,推荐在临床实践中广泛应用。
OBJECTIVE: To compare the effects of sequential chemoradiotherapy and chemotherapy alone in the treatment of elderly locally advanced non-small cell lung cancer. Methods: A total of 77 cases were selected from outpatients and discharged patients admitted to our hospital from July 2012 to August 2014. All patients met the diagnostic criteria of non-small cell lung cancer and were randomly divided into treatment group (38 cases) and control group 39 cases, the former group of patients with sequential radiotherapy and chemotherapy treatment, the latter group of patients treated with chemotherapy alone, compared the two groups of treatment and adverse reactions. Results: After a period of treatment, the total effective rate in the treatment group was 81.6%, which was significantly higher than that in the control group (P <0.05). Adverse reactions in both groups, the difference was not significant, P> 0.05. Conclusion: In the treatment of elderly patients with locally advanced non-small cell lung cancer, sequential chemoradiotherapy is more effective than chemotherapy alone in the treatment of locally advanced non-small cell lung cancer. The therapeutic effect is more significant, and its application value and promotion value are relatively high. It is recommended that it be widely used in clinical practice .