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应用免疫组织化学BA法探讨了123例乳腺癌患者预后与雌激素受体(ER)的关系。平均随访72个月(2个月~112个月)。结果显示ER(+)88例,术后复发转移19例,占21.6%,5年生存率74.4%,ER(-)组35例,术后转移复发15例,占42.9%,5年生存率52.3%。经统计学处理有显著性差异。提示ER(-)乳腺癌属相对高危组,预后差,术后复发转移率高,5年生存率低,ER(+)患者属相对低危组,其预后明显好于ER(-)组。
The relationship between prognosis and estrogen receptor (ER) in 123 breast cancer patients was studied by immunohistochemical BA method. The average follow-up period was 72 months (2 months to 112 months). The results showed 88 cases of ER (+), postoperative recurrence and metastasis in 19 cases, accounting for 21.6%, 5-year survival rate of 74.4%, ER (-) group of 35 cases, postoperative metastasis and recurrence of 15 cases, accounting for 42.9 %, 5-year survival rate 52.3%. Statistically significant differences. The ER (-) breast cancer is relatively high-risk group, poor prognosis, postoperative recurrence and metastasis rate, low 5-year survival rate, ER (+) patients are relatively low-risk group, its prognosis is significantly better than ER (-) group.