论文部分内容阅读
近来作者等人证明促肾上腺皮质素(ACTH)释放肽不仅限于垂体,而且也存在于中枢神经元和胃肠道的胃泌素分泌细胞内。在垂体的提取物中也检出有胃泌素(G)免疫反应活性存在。作者通过应用细胞免疫化学和放免对于垂体的显微解剖和分离垂体细胞的测定证明垂体胃泌素存在于ACTH类和α黑色细胞刺激素(α-MSH)类细胞内以及垂体柄的神经纤维和神经叶内。有意义量的胃泌素在垂体所有部分都被测到。对照之下胆囊收缩素(CCK)
Recently, the authors have shown that ACTH-releasing peptides are not limited to the pituitary gland but also exist in the central neurons and the gastrin secreting cells of the gastrointestinal tract. Gastrin (G) immunoreactivity was also detected in pituitary extracts. By applying immunocytochemistry and radioimmunoassay to pituitary microdissection and determination of pituitary cells, the authors demonstrated that pituitary gastrin is present in both ACTH and α-MSH-like cells and pituitary stalk nerve fibers and Inside the nerve leaf. A significant amount of gastrin is detected in all parts of the pituitary gland. In contrast, cholecystokinin (CCK)