论文部分内容阅读
[目的]探讨康复新联合兰索拉唑治疗非甾体抗炎药(NSIADs)相关性溃疡的疗效。[方法]将经胃镜确诊的76例NSAIDs相关性溃疡患者,随机分为2组,治疗组38例,应用康复新10 ml,3次/d,兰索拉唑30 mg,1次/d;对照组38例,应用兰索拉唑30 mg,1次/d,疗程均为4周。疗程结束后,记录症状转归,胃镜复查评估溃疡愈合情况。[结果]2组临床症状改善情况比较差异无统计学意义(P>0.05)。溃疡的愈合率和总有效率治疗组为94.7%和97.4%,对照组为78.9%和84.2%,2组比较差异有统计学意义(P<0.05)。[结论]康复新联合兰索拉唑治疗NSIADs相关性溃疡可提高溃疡的愈合率和总有效率。
[Objective] To investigate the curative effect of rehabilitation combined with lansoprazole on non-steroidal anti-inflammatory drugs (NSIADs) related ulcer. [Methods] 76 patients with NSAIDs related ulcer diagnosed by gastroscope were randomly divided into two groups. The treatment group was treated with 10 ml of rehabilitation, 3 times / d, lansoprazole 30 mg once daily, Control group, 38 cases, application of lansoprazole 30 mg, 1 / d, treatment were 4 weeks. After the end of treatment, the symptoms were recorded and gastroscopy was performed to evaluate the ulcer healing. [Results] There was no significant difference in the improvement of clinical symptoms between the two groups (P> 0.05). The healing rate and total effective rate of ulcer were 94.7% and 97.4% in the treatment group and 78.9% and 84.2% in the control group, respectively. The difference between the two groups was statistically significant (P <0.05). [Conclusion] Rehabilitation combined with lansoprazole in the treatment of NSIADs-related ulcer can improve the healing rate and total effective rate of ulcer.