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目的 :研究蚯蚓提取物 (EFE)的免疫活性及抗肿瘤作用。方法 :采用小鼠移植性肿瘤S1 80 肉瘤及Heps肝癌的动物模型观察其肿瘤抑制作用。结果 :EFE对S1 80 肉瘤和Heps肝癌细胞的抑制率分别为 36 97%和 4 8 55% ;结论 :它对小鼠实体瘤细胞有明显的抑制作用 (P <0 0 1 )并提示对小鼠的细胞和体液免疫功能有显著增强作用。
Objective: To study the immunological activity and anti-tumor effect of earthworm extract (EFE). Methods: Tumor suppressor effects were observed in animal models of S180 sarcoma and Heps hepatocellular carcinoma in mice. Results: The inhibitory rates of EFE on S180 sarcoma and Heps hepatocarcinoma cells were 36 97% and 485%, respectively. Conclusion: The inhibitory effect of EFE on S180 sarcoma cells and Heps hepatocarcinoma cells was significant (P <0.01) Rat cells and humoral immune function significantly enhanced.