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目的:对艾滋病合并肺感染下皮肤病的治疗效果进行观察。方法:选取我中心门诊2014年2月至2016年2月期间收治的46例艾滋病合并肺感染下皮肤病患者,随机分为观察组与对照组,各23例。对照组采用高效抗反转录病毒治疗,观察组在对照组治疗基础上联合复方甘草酸苷治疗,对两组患者治疗效果进行对比,对所有患者T细胞亚群情况进行观察。结果:在治疗银屑病、过敏性紫癜、荨麻疹、扁平苔藓及皮肤瘙痒症等治疗效果方面,观察组明显优于对照组,差异有统计学意义,P<0.05;在艾滋病T细胞亚群影响方面,观察组CD8~+CD38~+T细胞下降幅度明显高于对照组,差异有统计学意义,P<0.05;治疗6个月后,CD4~+T淋巴细胞计数方面,观察组升高幅度明显高于对照组,差异有统计学意义,P<0.05。结论:复方甘草酸苷辅助治疗艾滋病合并肺感染下皮肤病的效果较好,在临床中有推广应用的价值。
Objective: To observe the effect of treatment of skin diseases caused by AIDS complicated with pulmonary infection. Methods: Forty-six patients with AIDS-infected skin-acquired dermatitis were selected from our center clinic between February 2014 and February 2016. They were randomly divided into observation group and control group, with 23 cases in each group. The control group was treated with highly effective antiretroviral therapy. The observation group was treated with compound glycyrrhizin on the basis of the control group, and the treatment effect was compared between the two groups. The T cell subsets of all the patients were observed. Results: In the treatment of psoriasis, Henoch-Schonlein purpura, urticaria, lichen planus and pruritus and other therapeutic effects, the observation group was significantly better than the control group, the difference was statistically significant, P <0.05; in AIDS T cell subsets In the aspect of influence, the decrease of CD8 ~ + CD38 ~ + T cells in the observation group was significantly higher than that in the control group, the difference was statistically significant, P <0.05; After 6 months of treatment, CD4 ~ + T lymphocyte count, The amplitude was significantly higher than the control group, the difference was statistically significant, P <0.05. Conclusion: The compound glycyrrhizin adjuvant treatment of AIDS with pulmonary infection of the skin is better, in the clinical application of the value.