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目的探讨35岁以上人群颈动脉粥样硬化(CAS)与退行性心脏瓣膜病(DVHD)的相关性。方法应用整群随机抽样法抽取新疆地区13 896例35岁以上受检者,统计不同民族、性别、年龄人群中CAS和DVHD的患病率,并分析两者的相关性。结果 CAS患病率为35.5%,DVHD患病率为9.6%,两患病率均随年龄增加而逐渐升高,男性高于女性;哈萨克族64岁以下者CAS、DVHD患病率均低于哈萨克族和汉族,65岁以上者CAS、DVHD患病率均高于哈萨克族和汉族(P均<0.05)。患CAS者有更高的DVHD检出率,患DVHD者有更高的CAS检出率(P均<0.05)。结论新疆地区成年人CAS、DVHD患病率与年龄、性别及民族存在相关性;CAS与DVHD可能具有一定相关性。
Objective To investigate the association between carotid atherosclerosis (CAS) and degenerative heart valve disease (DVHD) in people over 35 years of age. Methods A total of 13 896 subjects over 35 years old from Xinjiang were enrolled in this study. The prevalence rates of CAS and DVHD in different ethnic groups, gender and age groups were calculated and the correlation between the two groups was analyzed. Results CAS prevalence was 35.5%, DVHD prevalence was 9.6%, both prevalence increased with age and increased in males than females; Kazakh under 64 years old CAS, DVHD prevalence were lower than Kazak and Han nationality, the prevalence of CAS and DVHD were higher than those of Kazak and Han over 65 years old (all P <0.05). Patients with CAS had a higher detection rate of DVHD and patients with DVHD had a higher CAS detection rate (all P <0.05). Conclusion The prevalence of CAS and DVHD among adults in Xinjiang is related to age, gender and ethnicity. CAS and DVHD may be related to each other.