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综述英国抗菌化学治疗学会(BSAC)、美国心脏协会(AHA)、欧洲心脏病学会(ESC)、英国心脏学会(BCS)等最近发布的感染性心内膜炎(IE)预防指南。由于尚无证据表明口腔科操作或手术时预防应用抗生素有益,因此,BSAC建议,在进行所有口腔科操作时,仅对IE高危患者给予抗生素预防:成人术前1h一次给予口服阿莫西林3g;对青霉素过敏者,术前1h一次给予口服克林霉素600mg。在进行泌尿生殖道、胃肠道、呼吸道及妇产科手术或操作时,对IE中高危患者联合应用阿莫西林及庆大霉素,术前或诱导麻醉时给药;对青霉素过敏者,联合应用替考拉宁及庆大霉素。
This review summarizes recent guidelines for the prevention of infective endocarditis (IE), including the British Society for Antibacterial Chemotherapy (BSAC), the American Heart Association (AHA), the European Society of Cardiology (ESC), the British Heart Association (BCS) Since there is no evidence that prophylactic use of antibiotics is appropriate for stomatological or surgical procedures, BSAC recommends that antibiotic prophylaxis be given only to IE-at-risk patients in all dental practices: 3 g orally administered amoxicillin is given once per day in adults; Those who are allergic to penicillin, given once before surgery clindamycin 600mg. In the genitourinary tract, gastrointestinal tract, respiratory and obstetrics and gynecology surgery or operation, the combination of high-risk patients with IE amoxicillin and gentamicin, preoperative or induction of anesthesia; penicillin allergy, Combination of teicoplanin and gentamicin.