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目的对我院第三代头孢菌类抗生素的临床应用情况进行研究和分析,对临床用药给予更加科学的指导。方法以我院2009年2月至2013年4月584例第三代头孢菌类抗生素应用患者为研究对象,对其临床资料进行回顾性分折。结果第三代头孢菌类抗生素近年来应用日益广泛,不良反应以消化道反应为主,存在少量皮疹及血管反应。所有患者处置及时有效,未发生严重后果。结论临床应用第三代头孢菌类抗生素应依据患者药敏试验及药物代谢动力学科学用药,减少不良反应和耐药性,确保用药安全有效。
Objective To study and analyze the clinical application of the third generation cephalosporin antibiotics in our hospital and give more scientific guidance to clinical medication. Methods From February 2009 to April 2013 in our hospital, 584 patients with third-generation cephalosporin antibiotics were studied, and their clinical data were retrospectively analyzed. Results The third-generation cephalosporin antibiotics have been widely used in recent years. The main adverse reactions are digestive tract reaction with a small amount of rash and vascular reaction. All patients treated promptly and effectively, without serious consequences. Conclusion The clinical application of third-generation cephalosporin antibiotics should be based on patients susceptibility testing and pharmacokinetics of scientific medication to reduce adverse reactions and drug resistance, to ensure safe and effective medication.