急性坏死性胰腺炎是外科常见急腹症,是因胰管梗阻、内压增高导致胰液外溢,使胰腺及其周围器官组织发生自体消化所致。近年来虽对本病病因、病理、临床特点、并发症及治疗进行了广泛研究,获得一些新的认识,但由于胰腺发炎坏死后,可释放出大量的酶和活性物质,不仅可引起水电解质、酸碱代谢及糖代谢紊乱,还可引起心、肺、肝、肾、脑等多器官功能衰竭(MOF),导此病死率增高,文献报告全胰坏死的死亡率达90～100％,节段性坏死死亡率达30～40％,术后死于继发脓肿占死亡总人数的75％。我院普外科于1983.1～1989.12。共收治急性坏死性胰腺炎(ANP)86例,其中男性44例,女性42例,年龄14～82岁,51岁以上有41例,占47.7％。手术死亡率高达40～80％,本 Acute necrotizing pancreatitis is a common acute abdomen surgery, is due to pancreatic duct obstruction, increased internal pressure resulting in pancreatic juice spill, pancreatic and its surrounding organs and tissues due to autodigestion. Although in recent years the etiology, pathology, clinical features, complications and treatment of this disease have been widely studied and gained some new understanding, but due to inflammation and necrosis of the pancreas can release a large number of enzymes and active substances, not only can cause water and electrolyte , Acid-base metabolism and glucose metabolism disorders, but also can cause heart, lung, liver, kidney, brain and other organ failure (MOF), leading to increased mortality, reported complete pancreatic necrosis death rate of 90 to 100% Segmental necrosis mortality rate of 30 to 40%, died of secondary abscess after surgery accounted for 75% of the total number of deaths. Our hospital general surgery in 1983.1 ~ 1989.12. A total of 86 cases of acute necrotizing pancreatitis (ANP) were treated, including 44 males and 42 females, aged from 14 to 82 years old, 41 cases over 51 years old, accounting for 47.7%. Surgical mortality rate as high as 40 ~ 80%, Ben