【摘 要】
：
目的 观察脂肪乳对地西泮中毒的血药浓度影响及临床疗效.方法用20%脂肪乳250 mL治疗5例地西泮中毒患者,动态监测Ramsay镇静深度评分和地西泮血药浓度,比较治疗前后不同时间点
论文部分内容阅读
目的 观察脂肪乳对地西泮中毒的血药浓度影响及临床疗效.方法用20%脂肪乳250 mL治疗5例地西泮中毒患者,动态监测Ramsay镇静深度评分和地西泮血药浓度,比较治疗前后不同时间点Ramsay镇静深度评分、地西泮实测血药浓度与理论代谢浓度之间的差异.结果 脂肪乳治疗2 h后,患者血液地西泮浓度有显著降低,治疗前后中毒药物浓度下降幅度远远大于其理论代谢状态下的下降幅度(554.6±369.4 vs 1883.6±811.5,P=0.002),治疗前后不同时间段Ramsay镇静深度评分差异有统计学意义[F=27.30;P=0.000;P=0.001(治疗前vs治疗后2 h);P=0.000(治疗前vs治疗后20 h);P=0.009(治疗后2 h vs治疗后20 h)].结论 小样本资料观察发现,脂肪乳可在短时间内显著降低地西泮血药浓度,改善中毒患者的意识状态,是值得进一步深入研究的脂溶性药物中毒潜在解毒剂.
其他文献
By the decomposition of copper nitrate at 400 ℃, oriented islands of copperoxide crystals were successfully fabricated on the amorphous glass surface. X-ray di
High performance Sm2Fe17Nx magnetic powders were fabricated by ball-milling method and were compacted using spark plasma sintering(SPS) technique.Effects of pro
Organic coatings are widely used to control the corrosion of steel structure. The anticorrosive property of these coatings depends on their barrier properties,
Ba 3Zn Z Co 2 Z Fe 24 O 41 /SiO 2 ( Z varies from 0.0 to 1.2 in step of 0.4) microcrystalline glass ceramics were prepared by citrate
Electropulse modification (EPM) process, a new physical field method for improving the solidification structure of metals was introduced.Different from other re
The surface nanostructures of commercial pure titanium was realized by the modified shot peening equipment commonly used in industry through the special treatme
医疗服务支付方式改革是医药卫生体制改革核心问题之一.支付方式能够影响医疗服务利益相关者的行为,从而对医疗费用、医疗质量、医疗服务效率和医疗保险资金使用的效益产生影
Solder balls, which are used in advanced electronics packages such as BGA (Ball Grid Array) and CSP (Chip Scale Package) to substitute the leads and realize the
目的 评价帕瑞昔布钠用于肺叶切除术病人超前镇痛的效果.方法 择期行开胸肺叶切除术病人60例,性别不限,年龄20～64岁,体重50～80 kg,ASA分级Ⅱ或Ⅲ级,采用随机数字表法,将患者
A kind of thermal spray nanostructured Al2O3 and TiO2 feeds fabricating technology was investigated.Agglomerated nanogranules prepared by spray drying were heat