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自孕早期绒毛取材进行产前诊断(CVS)的技术在70年代初创立以来,绒毛取材的器械不断改进,方法日趋增多。1984年Covone开始研究利用滋养叶细胞表面特异抗原,采用单克隆抗体技术,从母体外周血获取滋养叶细胞,但该技术目前仍处探索阶段。从宫颈内口冲洗抽吸,获取脱落绒毛组织用于产前诊断,虽安全性显著提高,然而取材成功率甚低。迄今为止,世界上具备实际可行性的绒毛取材术,还是经宫
The technique of prenatal diagnosis (CVS) of early harvest of villus from the first trimester Since its establishment in the early 1970s, the devices of villus harvesting have been continuously improved and methods are increasingly being developed. In 1984 Covone began to study the use of trophoblast cell surface antigen-specific monoclonal antibody technology to obtain trophoblast cells from maternal peripheral blood, but the technology is still in the exploratory stage. Flushing from the internal orifice of the cervix to obtain shedding villi for prenatal diagnosis, although the safety is significantly improved, but the success rate is very low. So far, the world has practical feasibility of hair harvesting, or by the palace