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目的:通过计算机声音分析技术比较研究哮喘患者发作时和治疗后的呼吸音变化。方法:对30例实验组患者在发病时和治疗完成后的呼吸音进行分析。另有12名呼吸系统正常的志愿者作为对照组做比较分析。分别记录声音的振动模式,并且分别对左、右肺的呼吸音进行记录分析。结果:研究发现哮喘发作时左、右肺的呼吸音振动能量峰(VEPs)具有不同步性。正常个体左、右肺VEPs几乎同步,呼气VEPs间隔(0.007±0.013)s,哮喘病患者间隔为(0.15±0.10)s,治疗后间隔可改善为(0.05±0.05)s。相比于正常个体,哮喘患者左、右肺的不同步性差异具有统计学意义(P<0.05)。结论:患者哮喘发作时左、右肺VEPs不同步性明显增加,经临床治疗后不同步性显著减少,因此对患者的呼吸音进行分析,可以用于哮喘病的临床诊查及疗效判断,值得进一步研究探讨和临床推广。
OBJECTIVE: To compare the changes of respiratory sounds at the onset of asthma and post-treatment by computer acoustics analysis. Methods: Thirty patients in the experimental group were analyzed at the onset and after treatment. Another 12 normal respiratory system volunteers as a control group for comparative analysis. Respectively record the vibration mode of sound, and left and right lung breath sounds were recorded and analyzed. RESULTS: The study found that the respiratory sounds vibrational energy peaks (VEPs) in the left and right lungs of asymptomatic asthmatic patients were asynchronous. The VEPs of the left and right lungs of the normal individuals were almost synchronous. The interval of VEPs was 0.007 ± 0.013 s, the interval of asthma was 0.15 ± 0.10 s, and the interval of treatment was improved to 0.05 ± 0.05 s. Compared with normal individuals, asthma patients left and right lungs asynchrony difference was statistically significant (P <0.05). Conclusions: The VEPs in the left and right lungs of patients with asthma attack increased significantly and their synchronism decreased significantly after they were treated. Therefore, the analysis of the patient’s breath sounds can be used for the clinical diagnosis and treatment of asthma. Further research and clinical promotion.