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用高汞水喂养大鼠８周，复制出慢性汞中毒模型，再分别自由饮用利康饮饮料和腹腔注射二巯基丙磺酸钠３周，探讨刺梨利康饮和二巯基丙磺酸钠对慢性汞中毒大鼠体内汞、铜、锌含量的影响。结果显示：慢性汞中毒引起血清、肝、脑和肾中汞含量升高的同时，引起血清、脑和肾中铜、锌含量及肝中锌含量降低；利康饮可降低血清和肾中汞含量，并可提高血清、脑和肾中铜、锌含量及肝中锌含量；二巯基丙磺酸钠虽可降低血清、肝和肾中汞含量，升高血清和肾中铜含量，但引起血清和肝中锌含量更加降低。结果表明：利康饮可降低慢性汞中毒大鼠体内汞的负荷量，并具有补充铜、锌微量元素的作用。
Rats were fed high-calcium water for 8 weeks and a chronic mercury poisoning model was replicated. Licor drinking beverages and intraperitoneal injections of sodium dimercaptopropane sulfonate were administered for 3 weeks to investigate the chronic effects of Zichong Likangyin and sodium dimercaptopropane sulfonate. Effects of Mercury, Copper and Zinc Contents in Rats with Mercury Poisoning. The results showed that: chronic mercury poisoning caused by elevated levels of mercury in serum, liver, brain and kidney, while causing serum, brain and kidney copper, zinc content and zinc in the liver decreased; Likang drink can reduce serum and renal mercury , and can increase the copper, zinc content in the serum, brain and kidney and the zinc content in the liver; DGMS can reduce the mercury content in the serum, liver and kidney, increase the serum and copper content in the kidney, but cause serum And the zinc content in the liver is even lower. The results showed that: Likangyin can reduce the mercury load in rats with chronic mercury poisoning, and has the function of supplementing trace elements of copper and zinc.