肾透明细胞癌增强CT征象与临床病理相关性研究

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目的:探讨肾透明细胞癌增强CT征象与其临床病理特征的相关性。方法:回顾性分析2015年1月至2019年1月湖州市第三人民医院行肾透明细胞癌根治术后患者33例的临床病理资料,利用Speraman相关性分析增强CT征象与病理特征的关系。结果:术后病理提示包膜侵犯17例,无包膜侵犯16例,两者在病灶直径、CT增强差值及增强率上的差异均有统计学意义[(7.74±1.85)cm比(4.15±1.41)cm,(30.19±10.00)HU比(48.25±24.12)HU,(70.7±22.6)%比(137.0±86.6)%,n t=-6.239、2.841、3.050,n P=0.000、0.008、0.005]。有脉管癌栓(12例)与无脉管癌栓(21例)患者的病灶直径及增强率上的差异均有统计学意义[(7.86±2.35)cm比(4.93±1.79)cm,(70.0±19.9)%比(121.0±81.7)%,n t=-4.025、2.074,n P=0.000、0.046],而CT增强差值差异无统计学意义[(30.78±11.71)HU比(43.62±22.63)HU,n t=1.823,n P=0.078]。Spearman相关性分析表明,CT增强差值与包膜侵犯及脉管癌栓呈中度负相关(n r=-0.593、-0.540,n P=0.000、0.001);病灶直径与包膜侵犯呈明显正相关(n r=0.781、n P=0.000)。n 结论:肾透明细胞癌病灶直径、CT增强差值及增强率有所差异,病灶直径越大、增强差值越小意味着包膜侵犯及脉管癌栓。“,”Objective:To investigate the correlation between enhanced CT features and clinicopathological features of renal clear cell carcinoma.Methods:The clinicopathological data of 33 patients with renal clear cell carcinoma after radical operation in the Third People′s Hospital of Huzhou from January 2015 to January 2019 were analyzed retrospectively.The relationship between enhanced CT signs and pathological features was analyzed by speraman correlation analysis.Results:The pathological findings showed that there were 17 cases of capsule invasion and 16 cases of no capsule invasion, and there were statistically significant differences in lesion diameter, CT enhancement difference and enhancement rate between the two groups[(7.74±1.85)cm vs.(4.15±1.41)cm, (30.19±10.00)HU vs.(48.25±24.12)HU, (70.7±22.6)% vs.(137.0±86.6)%, n t=-6.239, 2.841, 3.050, n P=0.000, 0.008, 0.005]. There were statistically significant differences in lesion diameter and enhancement rate between patients with vascular tumor thrombus (12 cases) and without vascular tumor thrombus(21 cases)[(7.86±2.35)cm vs.(4.93±1.79)cm, (70.0±19.9)% vs.(121.0±81.7)%, n t=-4.025, 2.074, n P=0.000, 0.046], but there was no statistically significant difference in CT enhancement difference[(30.78±11.71)HU vs.(43.62±22.63)HU, n t=1.823, n P=0.078]. Spearman correlation analysis showed that there was a moderate negative correlation between CT enhancement difference and capsule invasion and vascular carcinoma thrombus(n r=-0.593, -0.540, n P=0.000, 0.001). The diameter of the lesion was positively correlated with capsule invasion(n r=0.781, n P=0.000).n Conclusion:The diameter, CT enhancement difference and enhancement rate of renal clear cell carcinoma are different.The larger the diameter of the lesion and the smaller the enhancement difference indicate the capsule invasion and vascular carcinoma thrombus.
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