唐氏综合征是儿童智障的重要疾病之一,由于其存活生活不能自理、无法治疗而严重影响人口素质,给社会、家庭造成严重的精神和经济负担。研究和预防唐氏综合征是遗传工作者的重要社会责任。我室自2000年1月在门诊遗传中心就诊的5008例中,有314例的智障儿童,经检查染色体核型,异常 Down Syndrome is one of the most important diseases of children with mental retardation. Due to its inability to survive and to take care of life, Down’s syndrome can seriously affect the quality of the population and cause serious mental and financial burden on society and families. Down’s Syndrome research and prevention is an important social responsibility of genetic workers. Of the 5008 cases treated in our Outpatient Genetic Center since January 2000, 314 cases of mentally retarded children were examined for karyotypes and abnormalities