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目的探讨单纯疱疹毒性脑炎（HSVE）的临床表现及治疗现状。方法经ABC－ELISA法检测血和脑脊液单纯疱疹病毒抗体（HSVAb）确定的HSVE31例，男18例，女13例，平均年龄32±11岁。结果HSVE临床症状变异很大，有全身感染症状，脑膜刺激症状，脑症状，精神症状等。结论ELISA法检测HSV－1抗体对于HSVE早期诊断有一定价值，而PCR诊断HSVE较ELISA敏感性高，速度快，但PCR敏感性太高，极易造成假阳性，操作较复杂，ELISA法操作简便，宜于广泛应用。阿昔洛韦是目前治疗HSVE较理想的药物，但宜早期应用。
Objective To investigate the clinical manifestations and treatment of herpes simplex virus encephalitis (HSVE). Methods 31 cases of HSV confirmed by ABC-ELISA and HSV-HSV were enrolled in this study. There were 18 males and 13 females, with an average age of 32 ± 11 years. Results The clinical symptoms of HSVE varied greatly, with systemic infection symptoms, meningeal irritation symptoms, brain symptoms and mental symptoms. Conclusion HSV-1 antibody detection by ELISA is valuable for the early diagnosis of HSVV. HSV-PCR diagnosis of HSV is more sensitive and faster than ELISA, but the sensitivity of PCR is too high, which can easily lead to false-positive, complicated operation and simple ELISA. , Suitable for a wide range of applications. Acyclovir is currently the ideal treatment of HSVE drugs, but should be early application.