目的探讨地塞米松在漫单或慢闭术前应用对术后服部炎症抑制情况。方法对54例90眼慢单或侵闭患者，术前口服地塞米松1．5mg，每6小时1次，共4次。然后行巩膜瓣下咬切术，另78例126眼术前不用地塞米松作对照组。结果术后2周内地塞米松组眼压控制及视力改变显著优于对照组；炎症反应显著较轻。结论慢性青光眼术前用地塞米松可减轻术后眼部炎症反应。 Objective To investigate the effect of dexamethasone on the inflammation of postoperative clothes in patients with single or slow closure. Methods A total of 54 patients (90 eyes) with slow or single infiltration were enrolled. Preoperative oral dexamethasone (1.5 mg) was administered once every 6 hours for 4 times. Then scleral flap bite resection, another 78 cases without preoperative dexamethasone 126 as control group. Results Intraocular pressure control and visual acuity in dexamethasone group were significantly better than those in control group within 2 weeks after operation. Inflammatory reaction was significantly lighter. Conclusion Preoperative use of dexamethasone in chronic glaucoma can reduce postoperative ocular inflammatory response.