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目的对妊娠期糖尿病(GDM)的空腹血糖水平(FBG)与妊娠结局的相关性进行分析研究。方法 121例妊娠期糖尿病患者作为研究对象,根据75 g葡萄糖耐量试验(OGTT),将其中78例FBG正常者设为对照组,43例FBG升高者设为观察组,回顾分析其临床资料。结果观察组8例(18.6%)接受胰岛素治疗明显多于对照组5例(6.4%)(P<0.05);观察组产妇并发症发生率总计44.2%明显高于对照组16.3%(P<0.05),观察组新生儿高胆红素血症、新生儿窒息及巨大儿的发病率明显增加,与对照组比较差异具有统计学意义。结论妊娠期糖尿病患者空腹血糖水平升高会增加围生儿危险性,加强监测对改善母婴结局具有重要意义。
Objective To analyze the relationship between fasting plasma glucose (FBG) and pregnancy outcome in gestational diabetes mellitus (GDM). Methods 121 cases of gestational diabetes mellitus were enrolled in this study. According to 75 g glucose tolerance test (OGTT), 78 normal FBG patients were regarded as control group, and 43 cases FBG elevated patients as observation group. The clinical data were retrospectively analyzed. Results In the observation group, 8 cases (18.6%) received insulin therapy more than the control group (6.4%) (P <0.05). The incidence of maternal complications in the observation group was 44.2% significantly higher than that in the control group (P <0.05) ), The observation group neonatal hyperbilirubinemia, neonatal asphyxia and the incidence of macrosomia significantly increased compared with the control group was statistically significant. Conclusion The increase of fasting blood glucose in patients with gestational diabetes mellitus will increase the perinatal risk, strengthen the monitoring of the improvement of maternal and child outcomes is of great significance.