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目的 :探讨乳糖红霉素和地塞米松尿道灌注治疗沙眼衣原体 (CT)和 (或 )解脲脲原体 (UU )性尿道炎的疗效。方法 :筛选出 15 0例不并发淋病、附睾炎及前列腺炎 ,有尿道炎症状 ,尿道分泌物荧光聚合酶链反应检查CT和 (或 ) U U阳性病例 ,随机分为 3组 ,每组各 5 0例。服药组 ,口服福爱力红霉素 ;灌注组 ,用 1%乳糖红霉素和0 .5 %地塞米松作尿道灌注 ;对照组 ,尿道灌注生理盐水。10 d为 1个疗程。结果 :经过 1～ 2个疗程治疗 ,服药组治愈 31例 ,好转 4例 ,无效 15例 ;灌注组治愈 41例 ,好转 5例 ,无效 4例 ;对照组治愈 4例 ,好转 2例 ,无效 44例。结论 :尿道灌注治疗明显优于口服药物治疗 (P <0 .0 5 ) ,且无明显不良反应。
Objective: To investigate the efficacy of lactose erythromycin and dexamethasone urethral perfusion in the treatment of Chlamydia trachomatis (CT) and / or Ureaplasma urealyticum (UU). Methods: Fifty cases of non-concurrent gonorrhea, epididymitis and prostatitis were selected. Urethritis symptoms and urethral discharge were detected by fluorescence polymerase chain reaction. CT and / or UU positive cases were randomly divided into 3 groups of 5 0 cases. The medication group, oral erythromycin erythromycin; perfusion group, with 1% lactose erythromycin and 0.5% dexamethasone for urethral perfusion; control group, the urethral perfusion of saline. 10 d for a course of treatment. Results: After 1 to 2 courses of treatment, 31 cases were cured, 4 cases improved, 15 cases were ineffective; 41 cases were cured, 5 cases improved, 4 cases failed; 4 cases were cured, 2 cases improved, and 44 cases were ineffective example. Conclusion: The urethral perfusion therapy is obviously better than oral medication (P <0.05), and no obvious adverse reactions.