糖皮质激素被临床上广泛用于治疗溃疡性结肠炎 ,并可取得较为满意的疗效。但应用不当易产生诸多不良反应 ,较为常见的是因物质、水盐代谢紊乱引起的满月脸、向心性肥胖、皮肤变薄等类肾上腺皮质功能亢进综合征的表现 ,而继发严重的感染较为少见。现将我院近 3年来收治的 8例外 Glucocorticoids are widely used in clinical treatment of ulcerative colitis, and can obtain more satisfactory results. However, improper application prone to many adverse reactions, more common is due to substance, water and salt metabolism caused by full moon face, central obesity, skin thinning and other types of adrenal insufficiency syndrome, and secondary severe infection more Rare. Now my hospital admitted to the past three years, eight exceptions