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目的研究血清总蛋白(STP)、白蛋白(ALB)及淋巴细胞水平在老年肺结核患者临床诊疗中的价值。方法选取自2014年8月至2015年11月于沈阳市第十人民医院就诊并确诊为肺结核的老年患者117例,分为初治组和复治组。入院2 d内空腹抽血检测患者的STP、ALB和淋巴细胞水平。采集患者的即时痰、夜间痰与晨痰,然后选取标本进行检测。根据检测结果分析ALB和淋巴细胞水平之间的相关性。对初治组和复治组中的涂阴与涂阳患者的STP、ALB和淋巴细胞的减低情况进行分析对比。对比不同分组和不同性别的患者之间的白蛋白检测结果。结果在全部117名患者中,出现STP减低的有29人,占比24.79%;ALB减低的有51人,占比43.59%;淋巴细胞减低的有30人,占比26.64%。老年人肺结核中淋巴细胞水平和ALB存在正相关。初治组和复治组中,涂阴和涂阳患者ALB和淋巴细胞降低度比较差异有统计学意义(P<0.05),涂阳患者中出现的人次明显高于涂阴患者。初治组的男性患者中,涂阴患者的ALB情况明显高于涂阳患者。女性患者对比差异无统计学意义(P<0.05)。复治组的男性和女性患者中,涂阴患者的ALB情况均明显高于涂阳患者。结论未发现STP水平在老年肺结核患者的临床治疗中有重要价值,但ALB和淋巴细胞水平作为两种重要的营养评价指标,在老年肺结核患者的临床治疗中可以起到重要作用。
Objective To investigate the value of serum total protein (STP), albumin (ALB) and lymphocyte in clinical diagnosis and treatment of elderly patients with pulmonary tuberculosis. Methods A total of 117 senile patients diagnosed as pulmonary tuberculosis from the Tenth People’s Hospital of Shenyang City from August 2014 to November 2015 were selected and divided into initial treatment group and retreatment group. STP, ALB and lymphocyte levels were measured in fasting blood samples within 2 days of admission. Collecting patients with instant sputum, sputum and morning sputum at night, and then select the specimens for testing. The correlation between ALB and lymphocyte levels was analyzed based on the results of the tests. The reduction of STP, ALB and lymphocytes in the smear-positive and smear-positive patients in the untreated and retreated groups was analyzed and compared. Compare albumin test results between patients in different groups and with different genders. Results In all 117 patients, there were 29 patients with STP reduction, accounting for 24.79%; 51 patients with ALB reduction, accounting for 43.59%; and 30 patients with lymphopenia, accounting for 26.64%. Pulmonary tuberculosis in elderly patients with lymphocyte levels and ALB positive correlation. Among the newly diagnosed group and retreated group, the decrease of ALB and lymphocyte in smear-positive and smear-positive patients was statistically significant (P <0.05), and the number of smear-positive patients was significantly higher than that in smear-negative patients. Among the male patients in the newly diagnosed group, the prevalence of ALB in smear-negative patients was significantly higher than that in smear-positive patients. There was no significant difference between female patients (P <0.05). In the retreatment group of male and female patients, smear-negative patients with ALB were significantly higher than smear-positive patients. Conclusions STP levels have not been found to be of clinical value in the treatment of elderly patients with pulmonary tuberculosis. However, ALB and lymphocyte levels are two important nutritional indicators and may play an important role in the clinical treatment of elderly patients with pulmonary tuberculosis.