论文部分内容阅读
目的 探讨连续硬脊膜外腔吗啡镇痛 (CIEA)对前列腺切除术后镇痛效果和安全性。方法 选择 40例前列腺切除术后患者 ,随机分成两组 ,实验组 (CIEA) :术后 48h持续性经硬脊膜外腔导管注入吗啡 ( 0 2mg/h) ;对照组 (MI) :患者疼痛时肌肉注射哌替啶 5 0mg或其它解痉镇痛药。观察两组VAS测痛评分 ,膀胱痉挛次数、持续时间、停止冲洗时间 ,及心率、血压和呼吸频率等。结果 实验组较对照组具有镇痛效果显著 (P <0 0 1) ,膀胱痉挛次数少 ,持续时间短 ,发生率低 (P <0 0 1)等优点 ,实验组呼吸频率术后与术前无明显差异 ( P >0 0 5 ) ,恶心、呕吐、瘙痒等不良反应发生率低。结论 连续硬脊膜外腔小剂量吗啡镇痛对前列腺切除术后患者的镇痛效果良好、安全。
Objective To investigate the analgesic efficacy and safety of continuous epidural morphine analgesia (CIEA) after prostatectomy. Methods Forty patients with post-prostatectomy were randomly divided into two groups: experimental group (CIEA): morphine (0 2 mg / h) was given via epidural catheter 48 h after operation; control group (MI) When intramuscular injection of pethidine 50mg or other antispasmodic analgesics. VAS pain score, bladder spasm frequency, duration, stop flushing time, heart rate, blood pressure and respiratory rate were observed. Results Compared with the control group, the experimental group had significant analgesic effects (P <0.01), fewer bladder spasms, shorter duration and lower incidence (P <0.01). The respiratory rate of the experimental group was significantly higher than that of the preoperative No significant difference (P> 0.05), nausea, vomiting, itching and other adverse reactions. Conclusion Continuous epidural low dose morphine analgesia has a good and safe analgesic effect on post-prostatectomy patients.