论文部分内容阅读
目的对复方蔷薇红景天口服液的质量进行分析,完善口服液的质控标准。方法采用薄层色谱法对其口服液中的川芎进行了定性鉴别,以阿魏酸为指标,运用高效液相色谱法进行了含量测定。结果样品薄层色谱中,在与阿魏酸对照品、川芎对照药材相应的位置显相同颜色的斑点。阿魏酸的检测浓度在2.206~55.15μg/ml范围内与峰面积呈良好的线性关系(R2=0.999 9);平均加样回收率为97.85%~101.01%,RSD<1.74%(n=3)。结论质量控制方法简便、准确,所建标准可用于该品的质量控制。
Objective To analyze the quality of Rhodiola rosea oral liquid and improve the quality control standard of oral liquid. Methods Chuanxiong was identified by TLC in this study. The content of ferulic acid was determined by HPLC. Results Thin layer chromatography in the sample, and ferulic acid reference substance, Chuanxiong control drug corresponding position was the same color spots. The concentration of ferulic acid was linear with the peak area in the range of 2.206-55.15μg / ml (R2 = 0.999 9). The average recovery was 97.85% -101.01% with RSD <1.74% (n = 3 ). Conclusion The method of quality control is simple and accurate. The standards can be used for the quality control of the product.